What is Clinical Research?
Clinical research involves testing a new drug or treatment for a disease to see if it really works to help make people better. Many treatments we use today for most medical problems are the result of clinical research.
Why Is Clinical Research Important for Alzheimer's Disease?
Currently, there is no way to prevent or cure Alzheimer’s disease. Clinical research is the way researchers can find treatments that work and are safe. There will never be any good treatments without research. More people are always needed to be part of research studies. Volunteers help researchers better understand or treat Alzheimer’s disease. Most importantly, participating in research is a way to help others.
What Happens with Clinical Research?
There are many kinds of clinical research. Some types of research test new drugs. Other types test ways of giving care. Still others test things like physical activity or diet. In clinical research, people volunteer to be research "subjects." Some of the subjects will get the new treatment being tested. A "control group" will receive a placebo (sugar pill), or "usual care." The study then tests if the new treatment works better than the placebo or usual care.
Some research looks at people who already have Alzheimer's disease to see if the new treatment can make them better. Other studies test treatments to prevent Alzheimer's disease in people who don't yet have it.
Who Pays for Clinical Trials?
If you volunteer for research, the costs related to the study will usually be covered, but be sure to ask about it. Sometimes the research is run by a drug company. Other times it is run by a branch of the US government. Either way, covered costs usually include any drugs, lab tests, x-rays, and study visits with doctors and nurses.
Is Clinical Research Safe?
Because the treatments being tested are new, there is always a risk of problems. But, there are safeguards in place to keep the risk of problems as low as possible. There are often special experts that follow the study to quickly detect problems if they occur. Before you enroll in a study, you will be told about the risks, benefits, and costs. You will also be given time for questions. This process is called "informed consent." Never sign up unless you are sure you understand. It may help to bring home the consent form to review so you don't feel rushed into a decision.
What are the Risks of Being in Clinical Research?
The main risks include having bad effects from the treatment being tested or that the treatment might not work. After hearing about the risks, you can decide if it is right for you or the person you care for. If the person has advanced dementia and cannot give consent, their guardian or health care power of medical attorney will have to sign for them.
|What are the Benefits of Being in Clinical Research?
Can Everyone With Alzheimer's Disease Be In Clinical Research?
Every research study is different. You will be checked to see if you fit the specific study. Whether someone fits depends on their medical condition and whether they have early or advanced Alzheimer's disease. Some people may fit some research studies, but not others.
Where Can I Find Out About Clinical Research Near Me?
Alzheimer's disease research is taking place in hundreds of locations around the country. For information about Alzheimer's disease clinical research, contact the following:
- Alzheimer's Association TrialMatch or call (800) 272-3900
- National Institute on Aging, National Institutes of Health, U.S. Department of Health and Human Services
- Banner Alzheimer's Institute
Written by: Cynthia Vargo, Central Region Director, Alzheimer's Association, Desert Southwest Chapter